Skeletal Dysplasias
نویسندگان
چکیده
منابع مشابه
Skeletal Dysplasias
This is a good radiological text covering occult traumatic lesions of the cervical, lower thoracic, and lumbar spine, especially for residents in radiology, neurosurgery, neurology, and orthopedics. The book reviews a topic which has not been widely covered in the literature. The major emphasis of this expanded second edition is the cervical spine, comprising seven of its ten chapters. A new ch...
متن کاملDermatoglyphs in skeletal dysplasias.
Finger and palm print patterns (dermatoglyphs) are formed in very early pregnancy, at about the same time the limbs are developing, and their formation probably depends upon the surface contours of the palms and soles during morphogenesis. Dermatoglyphs are useful in skeletal dysplasias for the detection and study of syndactyly and symphalangism, for dating the onset and the dysplasias, for dem...
متن کاملGenetic heterogeneity in skeletal dysplasias.
Certain skeletal dysplasias represent excellent examples of genetic heterogeneity. Clinical recognition of their individual characteristics is a fundamental prerequisite for an understanding of their pathogenetic mechanisms and for the identification of their basic molecular defects.
متن کاملTherapeutic potential of CNP for skeletal dysplasias
Background We had revealed that C-type natriuretic peptide (CNP) is a potent stimulator of endochondral bone growth by using transgenic and knockout mice: transgenic mice with targeted overexpression of CNP in cartilage develop prominent skeletal overgrowth [1], whereas mice depleted with CNP exhibit impaired endochondral bone growth [2]. We planned to translate this effect of CNP into the ther...
متن کاملSkeletal Dysplasias: Growing Therapy for Growing Bones
Skeletal dysplasias represent a large and diverse group of rare conditions affecting collagen and bone. They can be clinically classified based on radiographic and physical features, and many can be further defined at a molecular level (Bonafe et al., 2015). Early diagnosis is critical to proper medical management including pharmacologic treatment when available. Patients with severe skeletal d...
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ژورنال
عنوان ژورنال: Clinics in Perinatology
سال: 2015
ISSN: 0095-5108
DOI: 10.1016/j.clp.2015.03.003